oloBion is a cutting edge laboratory located in the Barcelona Scientific Park.
Our goal is to help our customers gain new insight about the mode of action of their products or technology with our scientific platform based on mass spectrometry analysis.
Using our state-of-the-art instrument technology and our expert team, we deliver detailed reports revealing the chemistry behind life.
The name oloBion came from holobiont which is the ensemble of a plant or human with its microbiome. The interaction and communication at the molecular level between host and symbiont is the very basis of life.
The importance of Elements
The biological relevance of small molecules
The Greatest Wall
The Scent of Life
The Protection against the Cosmos
Proprietary Artificial Intelligence driven workflow for the interpretation of OMICS data
© 2023 oloBion, SL
Ionomics refers to the quantitative measurement of the complete set of ions in a living organism and deals with the changes in ion production under varied external stimuli. Biochemical pathways elucidate the production of ions that play a crucial role in maintaining cell integrity, transportation of minerals, and act as cofactors for enzymes catalyzing important regulatory pathways. Thus, alteration in the production of ions in a process can lead to large changes in metabolic pathways. It is very important to analyze the ions simultaneously as the production of some ions influence the production of other ions.
Questions within physiology, ecology, evolution, and many other fields can be investigated using ionomics, often coupled with other omics sciences.
Metabolites are the end products of cellular regulatory processes, and their levels can be regarded as the ultimate response of biological systems to genetic or environmental changes. The set of metabolites synthesized by a biological system constitute its ‘metabolome’.
We can identify two types of metabolism: primary and secondary.
A primary metabolite is a compound that is directly involved in normal growth, development, and reproduction. It usually performs a physiological function in the organism. For example, primary metabolites include amino acids, sugars, and organic acids.
Secondary metabolism (also called specialized metabolism) is a term for pathways and small molecule products of metabolism that are involved in ecological interactions, but are not absolutely required for the survival of the organism. Examples of secondary metabolites include: phenols, flavonoids, and alkaloids.
Lipids are extremely diverse molecules. This diversity of lipids creates complex biological systems with lipids acting as key components of cellular membranes, signaling molecules, and energy-storage molecules and substrates.
While lipidomics falls under the umbrella of metabolomics, identifying the hundreds of cellular lipid species requires distinct methods. Exploring the lipidome is important to understand cosmetics, mode of action in human skin, plant-pathogen interaction, and mechanism of diseases.
Volatolomics is a branch of chemistry that studies volatile organic compounds (VOCs) emitted by a biological system, under specific experimental conditions.
The volatilome is a part of the “microbial cloud” that surrounds all organisms and consists of aromatic compounds, alkyls, ketones, alcohols and esters.
Carotenoids are organic pigments that are produced by plants and algae, as well as by several bacteria and fungi.
There are over 1,100 known carotenoids that can be categorized into two main classes: xanthophylls (containing oxygen) and carotenes (which are purely hydrocarbons and contain no oxygen).
Carotenoids serve two key roles in plants and algae: they absorb light energy for use in photosynthesis and they provide photoprotection via non-photochemical quenching. Carotenoids that contain unsubstituted beta-ionone rings (including beta-carotene, alpha-carotene, beta-cryptoxanthin, and gamma-carotene) have vitamin A activity, meaning that they can be converted to retinol. In the eye, lutein, meso-zeaxanthin, and zeaxanthin are present as macular pigments whose importance in visual function.
oloMAP is our proprietary AI data processing and analysis pipeline to turn raw data into insights. We apply cutting-edge approaches to compound identification, chemical enrichment analysis, and metabolic pathway analysis to deliver an in-depth view of the chemical makeup of the samples alongside a high-level perspective of the chemical and biological mechanisms being exhibited. oloMAP is a self-improving workflow, continuously building upon its metabolomics chemical and spectral libraries so that we can apply today’s discoveries the next study tomorrow.
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