Metabolomics

about

About Metabolomics

Metabolomics is the large-scale analysis of small molecules (<1 kDa) involved in metabolism within cells, tissues, or organisms. It provides invaluable insights into physiological processes and potential pathological states. These molecules are essential for understanding cellular functions, metabolic pathways, and the delicate balance between health and disease. By exploring metabolite composition and dynamics, metabolomics serves as a powerful tool to decipher complex biological systems and advance precision medicine. 

Metabolomics is applied in fields such as healthcare for biomarker discovery and personalized medicine, microbiome research to study host-microbe interactions,  environmental science for pollutant analysis and agriculture for crop improvement. 

Global Profilling

Precise profiling of metabolic classes, structures and network interactions to provide a comprehensive understanding of metabolites diversity.

Tailored Precision Studies

Customize metabolic analyses to suit the unique needs of your research or industry, targeting a specific pathway or metabolite.

Efficacy Evaluation

Assess the impact of therapeutic interventions, dietary changes, or experimental conditions through precise analysis of metabolic shifts and responses.

Mechanistic Insights

Reveal mechanisms of action for diseases, treatments, or experimental compounds by mapping metabolic pathways and their regulation.

Biomarker Discovery

Identify and validate metabolite-based biomarkers for early disease detection, therapy monitoring, and personalized treatment strategies.

SERVICES

Our Metabolomics Services

At oloBion, we provide cutting-edge metabolomics services designed to empower researchers and industries, including Pharmaceutical & Biotechnology, Health & Medicine, Agriculture & Food, Cosmetics & Dermatology, Nutraceutical & Nutrition, Veterinary & Animal Science and Environmental & Ecology. With the support of advanced mass spectrometry platforms and the expertise of our team, we help you unlock the full potential of metabolite analysis, driving discovery, innovation, and impactful solutions. We offer both Untargeted and Targeted Metabolomics assays tailored to your specific needs.

Metabolomics Exposome Profile LC-MS

Technique: LC-MS/MS
Untargeted metabolomics analysis for the comprehensive profiling of exposome-related compounds, from environmental contaminants and xenobiotics to drugs and lifestyle markers, by LC-MS/MS. Identification output includes a tabulated list of each feature’s chemical superclass, class, compound name and InChIKey.

Metabolomics Compound Screening

Technique: LC-MS/MS
Untargeted metabolomics analysis for the identification of metabolites by LC-MS/MS. The Identification includes a list with superclass, class, metabolite name, and InChIKey.

Metabolomics Profile LC-MS

Technique: LC-MS/MS
Untargeted metabolomics analysis for the identification of metabolites by LC-MS/MS. The Identification includes a list with superclass, class, metabolite name, and InChIKey.

Metabolomics Profile GC-MS

Technique: GC-MS/MS
Untargeted metabolomics analysis for the identification of volatiles and metabolites by GC-MS/MS.The Identification includes a list with superclass, class, metabolite name, and InChIKey.

Metabolomics Volatiles GC-MS

Technique: GC-MS/MS
Untargeted metabolomics analysis for the identification of volatiles by GC-MS/MS. The Identification includes a list with superclass, class, metabolite name, and InChIKey.

MetaMetabolomics LC-MS

Technique: LC-MS/MS
Metabolomics analysis for the identification of active microorganisms through the study of secondary metabolism. The identification includes super-class, class, and name of the metabolite, InChIKey, and name of the microorganism. For fungi, it includes their guild and trophic mode

Central Carbon Metabolism LC-MS

Technique: LC-MS/MS
Untargeted LC-MS/MS metabolomics analysis for the identification of Central Carbon metabolites in plants, including organic acids and aminoacids. The Identification includes a list with superclass, class, metabolite name, and InChIKey.

Secondary Metabolism LC-MS

Technique: LC-MS/MS
Untargeted LC-MS/MS metabolomics analysis for the identification of secondary metabolites in plants. The identification includes a list with superclass, class, metabolite name, and InChIKey.

Pharmaco-Metabolomics

Is a key discipline in translational pharmacology, as it allows the analysis of drug impact on metabolism and helps understand variations in therapeutic response. Its integration enhances ADME-Tox studies and enables a more precise characterization of compound bioavailability, efficacy, and toxicity. 

Selection of relevant Metabolites and Biomarkers

  • Identify key metabolic classes: 
    • Amino acids (biomarkers of energy and protein metabolism)
    • Organic acids (involved in key metabolic pathways such as the Krebs cycle) 
    • Lipid metabolites (involved in inflammation and cell signaling) 
  • Identify pharmacometabolomic biomarkers associated with toxicity, bioavailability, and therapeutic efficacy. 

Panel: NAD LC-MS

Technique: LC-MS/MS
Metabolomics analysis for the identification and quantification of NAD-related metabolites: 1MNA 1-methylnicotinamide, 2PY N-methyl-2-pyridone-5-carboxamide, 3HAA 3-hydroxyanthranilic acid, 3HK 3-hydroxykynurenine, 4PA 4-pyridoxic acid/4PY N-methyl-4-pyridone-5-carboxamide, AA Anthranilic acid, CR Creatinine, KA kynurenic acid, KYN L-kynurenine, NA Nicotinic acid, NAAD Nicotinic acid adenine dinucleotide, NAD+Oxidized nicotinamide adenine dinucleotide, NADH Reduced nicotinamide adenine dinucleotide, NADP+ Oxidized nicotinamide adenine dinucleotide phosphate, NAM Nicotinamide, NAMN Nicotinic acid mononucleotide, NAMPT Nicotinamide phosphoribosyltransferase, NAR Nicotinic acid riboside, NR Nicotinamide riboside, PL Pyridoxal, PLP Pyridoxal 5′ -phosphate, PM Pyridoxamine, PN Pyridoxine, QA Quinolinic acid, TRP Tryptophan, XA Xanthurenic acid

Panel: Aminoacids LC-MS

Technique: LC-MS/MS

Metabolomics analysis for the identification and quantification of amino acids: L-Alanine, L-Arginine, L-Aspartic acid, L-Cystine, L-Glutamic acid, Glycine, L-Histidine, L-Isoleucine, L-Leucine, L-Lysine, L-Methionine, L-Phenylalanine, L-Proline, L-Serine, L-Threonine, L-Tyrosine, L-Valine, L-Tryptophan

Panel: Organic Acids LC-MS

Technique: LC-MS/MS

Metabolomics analysis for the identification and quantification of organic acids: Acetic acid, Adipic acid, L-Ascorbic acid, Benzoic acid, Butyric acid, Citric acid, Isobutyric acid, Formic acid, Fumaric acid, L-(+)-Lactic acid, DL-Isocitric acid trisodium salt hydrate, Maleic acid, Malonic acid, D-(+)-Malic acid, Oxalic acid, Phytic acid, Propionic acid, (-)Quinic acid, Succinic acid, Shikimic acid, D-(−)-Tartaric acid

Custom LC-MS

Technique: LC-MS/MS
Target Metabolomics analysis for the identification of specific metabolites(s) according to customer requirements

Enhance your analysis with:

How we work

From Samples to Insights

01

Contact and Proposal

Contact and

Proposal

02

Send Samples to the Lab

Send Samples
to the Lab

03

Frame 152

Sample Reception

and Processing

04

data usage 2

Mass Spectrometry

Analysis

05

Gain Insight into oloMAP Portal

Gain Insight into

oloMAP Portal

package

Standard Delivery Time:
6 weeks
Fast-track option available

labs

Minimum Sample Amount:
Consult our experts for guidance
on sample requirements

savings

Discount:
Associated with the number of
samples and multi-omics analysis

Get in Touch!

contact

Get in Touch!

Partner with us to explore the power of metabolomics in your field. Our team is ready to guide you through the process and deliver insights tailored to your research or industry needs.

Contact us today to discuss your project or schedule a consultation. Together, we’ll advance innovation through metabolomics!

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