Technique: Proximity Extension Assay (PEA) coupled with qPCR, readout pg/mL.
Target Proteomics analysis for the identification of 20 specific proteins. Interferon (IFN) inflammation is associated with immunotherapy resistance in melanoma. This panel is developed together with Dr. Mehta and is based on findings from the Nature Immunology paper “In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer” (Manguso et al.)